Measurement of Mitral Regurgitation in Man from Simultaneous Atrial and Arterial Dilution Curves after Ventricular Injection

Measurement of mitral regurgitation in man from simultaneous atrial and arterial dilution curves after ventricular injection.

THE MOST DIRECT APPROACH to measurement of the volume of blood regurgitating across an insufficient mitral valve consists of the injection of indicator into the left ventricle and simultaneous sampling of blood from the left atrium and from the aorta or one of its branches. If mixing is complete in the left ventricle, the distribution of indicator to upstream and downstream collection sites is ...

Detection and assessment of mitral regurgitation by left atrial indicator-dilution curves.

IX THE CONTINUING search for an accurate method of assessing mitral regurgitation, an indicator has been injected into the left ventricle, and the subsequent dilution curves have been recorded from both the left atrium and a peripheral artery. ' With increasing mitral regurgitation, an increasing concentration of early appearing dye can be detected in the left atrium, when normally there is lit...

Assessment of mitral regurgitation by dye dilution curves.

Hering (1829, 1832) obtained circulation times by detecting injected samples of potassium ferrocyanide by the Prussian Blue reaction, as quoted by Dow (1956). Stewart (1894) extended the work of Hering and was able to measure the cardiac output by a quantitative determination of the dilution of a solution of salt injected intravenously. It has taken many years since Stewart's time for the indic...

Effects of quantitatively controlled left ventricular-atrial regurgitation on indicator-dilution curves in the dog.

Measurement of mitral regurgitation by indicator-dilution techniques.

CONSIDERABLE progress has been made in recent years in the quantitative estimation of certain cardiovalvular abnormalities by cardiac catheterization.' The quantitative determination of mitral regurgitation has not yet reached a similar status despite a substantial amount of experimental effort. This article will give theoretical bases for determination of mitral regurgitation by indicator-dilu...